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High capacity capture, along with selective and efficient polishing steps are the main criteria for a robust protein purification platform. Up to now, purification processes have traditionally acted as a barrier to innovation due to:
In this webinar, the benefits of Pall’s chromatography process, which features Kaneka KanCapA♦, Mustang® Q and CMM HyperCel™ sorbents will be presented with a focus on the specificity of CMM HyperCel sorbent versus traditional cation exchangers or other mixed mode resins. This three-step process can be operated without any need for diafiltration or dilution between the chromatography steps.
We will demonstrate the robust performance of the CMM HyperCel sorbent within a streamlined batch process, which consistently provided purified mAb with high yield and purity > 95% yield with < 0.5% aggregates and < 15ppm HCP). The results of our investigation show the versatility of CMM HyperCel sorbent which provides flexibility within the development of a process whilst delivering high yield and purity of mAbs and recombinant proteins.
Duration: 1 hour
Best practices through implementation of the Biotech Integrated Solutions service architecture for large-scale manufacturing projects.